Stop looking for a needle in a haystack – Easily accelerate biomarker and target discovery by exploring and interpreting your data with intuitive, visual biomarker identification too.Single-Cell Genomic Solutions – Explore our powerful solutions for the analysis and interpretation of single-cell gene expression analysis and genomics.Pharmaceutical Development – Whether searching for clinically applicable biomarkers, designing a new companion diagnostic (CDx), or honing your study accrual and go-to-m.Research & Discovery – Powerful digital insights to help you innovate, integrate and translate scientific results into impactful discoveries.You can create, select, and delete the Workspace. Workspaces are saved automatically when you close the Main Workbench.You can switch between different workspaces. You might want to save this arrangement of viewing, it is called Workspaces. Workspace: While working on a project, you may view it in different ways.The selected tab at the top of the View Area shows the type of viewing active. View Area: On the right side of the page.The data elements saved in file locations are listed here. Navigation Area: On the top left side of the page.It consists of three tabs- Processes (list of tasks accomplished and pending), Toolbox (the list of workflows and analysis tools), and Favorites (most used tools are listed here). Toolbox Area: On the bottom left area of the page.It displays the status of Workbench and connection with other systems. Status bar: Top left side of the page.It includes all the tools related to the analysis. Many actions related to the tasks can be found here. Menu bar: On the topmost left side of the page.The main domains of the user area include: The CLC Main Workbench is simple and easy to use. The splendid user experience comes from a fabulous user interface. This leads to the development of “ supergenes” that helps in phylogenetic inferences. CLC Main Workbench allows you to join several sequences together after editing.You can also estimate the half-life and extinction coefficient. For protein sequences, molecular weight, isoelectric points, and aliphatic index can be calculated.There are two methods- individual statistics layout and comparative statistics layout. CLC Main Workbench allows you to find the relevant numbers and figures for any two sequences or more. The general sequence statistics can also be calculated.It is a measure of the diversity in amino acid composition in a protein sequence. You can also calculate the local complexity for both DNA and protein sequences.They are a powerful visual representation for comparing two sequences. You can extract the sequences, shuffle them, align them, and view them. This list of tools lets you analyze the sequences and molecules in a broadway. A minimap is an interesting tool that helps in viewing the tree in a very small area.It can be saved for every tree construction you perform in the future. You can always adjust the tree layout settings.Another method of tree construction is the Maximum Likelihood phylogenetic tree.After construction, you can check the reliability of the result by Bootstrapping. You can construct the tree by these two methods- UPGMA and Neighbourhood Joining method.CLC Main Workbench phylogenetic tree editor allows you to have- circular and radial layouts, data import in CSV format, a tabular representation of metadata, collapsing nodes based on bootstrap values, re-arranging the nodes, visualization of metadata, coloring, and labeling of trees, curved edges, editable nodes, and line size, etc.The phylogenetic tree construction makes the understanding of such relations easier. This is a key aspect in understanding the ancient genetic relations between different groups of organisms. Given below is a biomolecule structure generated from PDB 2R9R.
A file with information on 3D Coordinates only can be used to generate entire structures.
You can BLAST search the structure file against the PDB database.The visualization settings include- hydrogens, fog, clipping plane, 3D projection, coloring, etc. The visualization can be customized with different colors and styles of representation. You can view the protein structure in 3D.It allows the importing of molecule structure files from the Protein Data Bank (PDB) or its file in the system.